Stuart McCloskey and Josh van der Flier will make their Test debuts on Saturday as Ireland travel to Twickenham to take on England in the third round of the Six Nations.
Ulster‘s McCloskey comes in at inside centre in place of injured club teammate Jared Payne who has not recovered from the hamstring injury he suffered in the 10-9 defeat to France.
McCloskey’s including means Robbie Henshaw shifts to outside centre while Keith Earls is on the wing in the absence of injured Dave Kearney.
The inclusion of Leinster‘s Van der Flier is also due to injury and, like McCloskey, he replaces one of his club teammate, Sean O’Brien.
Ireland: Rob Kearney; Andrew Trimble, Robbie Henshaw, Stuart McCloskey, Keith Earls; Jonathan Sexton, Conor Murray; Jack McGrath, Rory Best (Capt.), Mike Ross; Donnacha Ryan, Devin Toner; CJ Stander, Josh van der Flier, Jamie Heaslip
Replacements: Richard Strauss, Cian Healy, Nathan White, Ultane Dillane, Rhys Ruddock, Eoin Reddan, Ian Madigan, Simon Zebo
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