Danny Cipriani will start the for the first time in the Sale Sharks jersey when they face Leinster in their new Salford City stadium.
New signings Richie Gray, Corne Uys and Eifion Lewis-Roberts are also named in the starting XV, with Mark Cueto and Andy Powell making first pre-season appearances.
Isa Nacewa will start for the first time this season for the Heineken Cup champions – who are missing most of their big names.
Sale Sharks: Rob Miller; Charlie Amesbury, Corne Uys, Johnny Leota, Mark Cueto; Danny Cipriani, Dwayne Peel; Eifion Lewis-Roberts, Marc Jones, Vadim Cobilas; Fraser McKenzie, Richie Gray; Mark Easter, David Seymour, Andy Powell.
Replacements: Joe Ward, Tony Buckley, Aston Croall, Kearnan Myall, Richie Vernon, Tom Holmes, Will Cliff, Nick Macleod, Sam Tuitupou, Will Addison, Charlie Ingall.
Leinster: Isa Nacewa; Andrew Conway, Brendan Macken, Noel Reid, Fionn Carr; Ian Madigan, Isaac Boss; Heinke van der Merwe, Richardt Strauss, Jamie Hagan; Tom Denton, Devin Toner; Dominic Ryan, Jordi Murphy, Leo Auva’a.
Replacements: Aaron Dundon, Jack McGrath, Martin Moore, Leo Cullen, Ben Marshall, John Cooney, Collie O’Shea, Jordan Coghlan, Darren Hudson, Jack O’Connell.