Niall O’Connor will run out in the number 10 jersey at Ravenhill for the first time since his short term spell in Galway last season and will be looking to take charge of a young and energetic backline.
Luke Marshall and Chris Farell form a new partnership in the centres hoping to unleash speedsters Craig Gilroy and Michael Allen on the wings.
New singing Nick Williams will start for the first time at No.8 since arriving from New Zealand.
Ulster: J Payne; C Gilroy, C Farrell, L Marshall; M Allen; N O’Connor, M Heaney; C Black, N Brady, D Fitzpatrick; J Muller (capt), L Stevenson; R Diack, A Birch, N Williams.
Replacements: R Lutton, R Herring, N Annett, J Afoa, A Macklin, N McComb, M McComish, S Doyle, B McIlroy, P Jackson, C Cochrane, S Olding, R Andrews, P Nelson.