Josh Beaumont, Nathan Hughes, Kyle Sinckler and Ben Te’o are in line for their Test debut after being retained in Eddie Jones‘ 25-man squad to prepare for Saturday’s Test against South Africa at Twickenham.
Forwards Charlie Ewels (Bath), Ellis Genge (Leicester), Teimana Harrison (Northampton) and Ben Morgan (Gloucester) return to their clubs.
As do backs Alex Goode (Saracens), Mike Haley (Sale), Alex Lozowski (Saracens), Semesa Rokoduguni (Bath) and Henry Slade (Exeter).
Jones will name his side to face South Africa on Thursday for the first of four games this autumn.
England squad:
Forwards (15): Josh Beaumont (Sale), Dave Attwood (Bath), Dan Cole (Leicester), Jamie George (Saracens), Dylan Hartley (Northampton), Nathan Hughes (Wasps), Joe Launchbury (Wasps), Courtney Lawes (Northampton), Joe Marler (Harlequins), Chris Robshaw (Harlequins), Kyle Sinckler (Harlequins), Tommy Taylor (Wasps), Billy Vunipola (Saracens), Mako Vunipola (Saracens), Tom Wood (Northampton)
Backs (10): Mike Brown (Harlequins), Danny Care (Harlequins), Elliot Daly (Wasps), Owen Farrell (Saracens), George Ford (Bath), Jonathan Joseph (Bath), Jonny May (Gloucester), Ben Te’o (Worcester), Marland Yarde (Harlequins), Ben Youngs (Leicester)