South Africa centre Frans Steyn will play in his 50thTest for the Springboks when they face Argentina on Saturday at Newlands in Cape Town.
The 25-year-old, who made his debut against Ireland in 2006, will become the 23rd player to reach 50 Test caps for South Africa.
Inside him, Morne Steyn retained his place at fly-half despite his below-par displays in the summer Test series against England in June.
In the only other changes from the team that played England in Port Elizabeth, Willem Alberts returns to flank in the place of Jacques Potgieter, who is on the bench, while Zane Kirchner is back at full-back for Gio Aplon.
Alberts is part of the six-man contingent from the Sharks who provide the entire front and back row following their strong performances that helped them reached the Super Rugby final.
South Africa: Zane Kirchner; Lwazi Mvovo, Jean de Villiers (captain), Frans Steyn, Bryan Habana; Morné Steyn, Francois Hougaard; Tendai Mtawarira, Bismarck du Plessis, Jannie du Plessis; Eben Etzebeth, Andries Bekker; Marcell Coetzee, Willem Alberts, Keegan Daniel.
Replacements: Adriaan Strauss, Pat Cilliers, Flip van der Merwe, Jacques Potgieter, Ruan Pienaar, Pat Lambie, JJ Engelbrecht.