Tyler Morgan will start at outside centre in Wales’ World Cup quarter-final against South Africa at Twickenham on Saturday.
The twice-capped 20 year-old got the nod over veteran James Hook who starts on the bench once again.
Gethin Jenkins returns for Paul James at loosehead and Dan Lydiate is recalled in the back-row in the place of Justin Tipuric.
George North who started in the No.13 shirt in the defeat to Australia last weekend returns to wing.
Wales coach Warren Gatland said: “After coming through an incredibly tough Pool, we are excited to be in the quarter-finals and returning to Twickenham.
“The physicality and intensity of the matches so far will stand us in good stead for what is going to be a huge battle against the Springboks.
“They have grown game on game in this tournament and we know the challenge that faces us from a talented South African side.”
Wales: Gareth Anscombe (Cardiff Blues), Alex Cuthbert (Cardiff Blues), Tyler Morgan (Newport Gwent Dragons), Jamie Roberts (Harlequins), George North (Northampton Saints); Dan Biggar (Ospreys), Gareth Davies (Scarlets); Gethin Jenkins (Cardiff Blues), Scott Baldwin (Ospreys), Samson Lee (Scarlets), Luke Charteris (Racing 92), Alun Wyn Jones (Ospreys), Dan Lydiate (Ospreys), Sam Warburton (Cardiff Blues, Capt.), Taulupe Faletau (Newport Gwent Dragons).
Replacements: Ken Owens (Scarlets), Paul James (Ospreys), Tomas Francis (Exeter Chiefs), Bradley Davies (Wasps), Justin Tipuric (Ospreys), Lloyd Williams (Cardiff Blues), Rhys Priestland (Bath Rugby), James Hook (Gloucester Rugby).
