Leicester will kick-off the Champions Cup season by hosting Stade Francais at Welford Road on November 13.
The clash between the Tigers and the Top14 champions will be a repeat of the 2001 Heineken Cup.
In the pool of death, both Bath and Wasps will be on the road to reigning champions Toulon and Leinster respectively.
Premiership champions Saracens will host old rivals Toulouse while Northampton will be at home to the Scarlets.
Finally Exeter will conclude the round 1 fixtures with a trip to the Ospreys on November 15.
The clash of the titans between Toulon and Leinster will take place in the back-to-back rounds in December with Toulon hosting the first leg on the 13th.
Harlequins will kick-off the European season with their Challenge Cup clash against Montpellier taking place on Thursday, November 12.
Last season’s winners, Gloucester, open their campaign against Zebre at Kingsholm Stadium on the while London Irish and Worcester will also be at home to Agen and La Rochelle.
Sale will be the only English side on the road for the opening weekend with a trip to Newport to take on the Dragons.
The dates and kick-off times for the Round 5 and 6 fixtures in both the Champions Cup and the Challenge Cup will be announced following the completion of the Round 4 games.
For the full Champions Cup fixtures, click here.
For the full Challenge Cup fixtures, click here.
Tourrnament weekends
Round 1: 12/13/14/15 November
Round 2: 19/20/21/22 November
Round 3: 10/11/12/13 December
Round 4: 17/18/19/20 December
Round 5: 14/15/16/17 January 2016
Round 6: 21/22/23/24 January 2016
Quarter-finals: 7/8/9/10 April 2016
Semi-finals: 22/23/24 April 2016
LYON 2016 FINALS
Challenge Cup – Friday 13 May 2016; Grand Stade de Lyon (21.00)
Champions Cup – Saturday 14 May 2016; Grand Stade de Lyon (17.45)
